New & Improved!

Due to high popularity and customer interest, we’ve reformulated & replaced our Pure NAD⁺ Micromist Nasal Spray.

Introducing our new NAD⁺ Complete Nasal Spray, which contains a powerful combination of Liposomal NAD,⁺ NMN & NR, which is fast-acting and easily absorbed by the body.

Why Intranasal Delivery Is Highly Effective

Intranasal delivery is one of the quickest and most effective ways to deliver NAD⁺ and its precursors, NMN and NR, into the body. The nasal mucosa’s rich blood flow allows for optimal drug absorption while avoiding the first-pass effect. ⑴

The first pass effect refers to drugs getting metabolized at specification locations in the body, most often the liver, which results in the drug’s reduced concentration in systemic circulation or at the target site.

“The intranasal administration is an effective way to systemically deliver drugs as an alternative to oral and intravascular routes.” ⑵

Improving NAD⁺ Levels for Better Health

As you age, your levels of NAD⁺ decline and as a result, you may begin to suffer from ageing-related illnesses, fatigue, metabolic issues and inflammation. Keeping levels of NAD⁺ high can help stave off these ageing-related problems.

Many people report improvements in overall health, energy levels, metabolism, fitness & improved sleep while taking NAD,⁺ NAD⁺ precursors & NAD⁺ optimiser supplements.

While there is a lot of uncertainty about the pathways NAD⁺ and NAD⁺ precursors take in the body, we do know that there are differences between them, and they have an affinity for different tissues. We believe the most effective protocol to increase NAD⁺ is through targeting all of these pathways.

Customer Experiences

Feedback from our customers is very important to us, and that’s why we conduct numerous product-related studies with our customers. We’ve received many reports of a quick boost in energy and mental clarity when using our nasal spray products, and an even stronger effect with our newest formulation here.

NAD+ Can Cross the Blood-Brain Barrier

As a protective layer surrounding the brain, the blood-brain barrier’s main purpose is to prevent harmful agents from reaching the brain. Research has shown that certain methods can be used to create a passageway through the barrier in order to allow therapeutic agents to reach their target.

In a study published in September of 2018, NAD⁺ was administered through Intraperitoneal Injection and Intravenous injection in mice. The injections demonstrated that NAD⁺ crosses the blood-brain barrier to enter the hypothalamus intact, in mice.

“In conclusion, our results demonstrate that exogenous NAD⁺ is effectively imported into the hypothalamus and increases hypothalamic NAD content.” ⑶ 

Neuroprotection from Intransal NAD+ Delivery

In one study on rats with transient focal ischemia, intranasal administration of NAD⁺ was found to significantly increase NAD⁺ levels in the brain, while being neuroprotective.

“We observed that intranasal NAD+ delivery significantly increased NAD+ contents in the brains.”

Intranasal Liposomal Delivery Improves Bioavailability

Intranasal liposomal delivery of NAD,⁺ NMN and NR improves bioavailability by encapsulating and delivering the compounds in their complete form for increased cellular uptake.

“Furthermore, the drugs administered using nasal route have usually higher bioavailability, less side effects and result in higher brain exposure at similar dosage than the oral drugs.” ⑷